Read e-book online An Atlas of Gross Pathology PDF

By Christopher D. M. Fletcher, Philip H. McKee

ISBN-10: 0713145579

ISBN-13: 9780713145571

ISBN-10: 0906923476

ISBN-13: 9780906923474

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Extra resources for An Atlas of Gross Pathology

Sample text

They occur in the large bowel and may be found at any age, but are espe cially common from the 5th decade onward s. Th ey are usually mul tiple, small, flat or sessi le and arise most often in the rectu m. They have no malignant potential. f1,"I1'I ,II P'I' Il h" l! 46 Villous adenoma. This example btl'l 1)11"" I ,Ii, race to show that it is a large, broad-bassrl :1,'" ', 01,, 1"', 1 whi c h numerous irregular papillary frond s projoCi N, II .. ",'"" h"" ",' :tllm may somelimes secrele large amOllnl ' , 01I" ,I ", ,I ,01 1"" n,n, giving rise to symptoms of hypokflli 1( 1" 11,' , II I'VI ' 1IIIII'"';tcm,a .

5 Giant fibroadenoma (Phyllodes tumour). Within the breast tissue is a large, lobulated mass showing myxoid, haemorrhagic and cystic foci. These tumours are relatively uncommon, occur predomi­ nantly in the 5th and 6th decades and may attain a great size . They are probably unrelated to the more common fibroadenomas (see page 45). Despite their obsolete name, cystosarcoma phyllodes, only about 5% behave in a malignant fashion .

This pancreas contains multiple, irregular pale masses of tumour, the largest of which is in the tail of the gland. The majority of islet cell tumours are, in fact , benign, the commonest being an adenoma of rl cells giving rise to hyper­ insulinism. Other adenomas may secrete glucagon (0. cells), somatostatin (8 cells), gastrin (perhaps from 8 cells), pancreatic polypeptide or vasoactive intestinal polypeptide . Islet cell tumours may form part of the Type I Multiple Endocrine Neoplasia Syndrome.

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An Atlas of Gross Pathology by Christopher D. M. Fletcher, Philip H. McKee

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