By Matthew J. Schniederjan MD, Daniel J. Brat MD PhD
It is a functional advisor and concise reference that may be a significant other textual content for the final surgical pathologist, trainees in pathology and neuropathology, and clinicians who deal with sufferers with neurological ailments that require surgical sampling.
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Extra info for Biopsy Interpretation of the Central Nervous System
Large, multiloculated examples are less common and are termed racemose lesions, referring to their grape-cluster appearance . Tissue sections of the cyst wall show a three-layered rind with a dense outer cuticle overlying a cellular band of small pinpoint nuclei and a loose inner reticulum with branching tubular canaliculi (Figure 2-16) . The body, or scolex, is a nodular protrusion into the cyst and microscopically displays internal organs and sharp chitinous hooklets that surround the organism’s mouth.
4. , Prolonged interval between sentinel pseudotumoral demyelination and development of primary CNS lymphoma. J Clin Neurosci. 2007;14(11):1126–9. 5. Joseph, FG, and NJ Scolding, Neurosarcoidosis: a study of 30 new cases. J Neurol Neurosurg Psychiatry. 2009;80(3):297–304. 6. Pawate, S, H Moses, and S Sriram, Presentations and outcomes of neurosarcoidosis: a study of 54 cases. QJM. 2009;102(7):449–60. 7. , Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization.
Although CNS involvement is thought to be the most severe form of tuberculosis, each of these types of infection is amenable to treatment with antibiotics. Surgery may be indicated in large mass lesions, or if CSF flow is compromised . The meningitis consists of a gelatinous, translucent suspension of lymphocytes, monocytes, and small caseous granulomas that extends slowly throughout the basal meninges, although any location is susceptible. Over time, fibrosis firms the affected area. Biopsy plays no significant role in diagnosing this meningitis.
Biopsy Interpretation of the Central Nervous System by Matthew J. Schniederjan MD, Daniel J. Brat MD PhD