By Giuseppe Moruzzi, Alfred Fessard and Herbert H. Jasper (Eds.)
ISBN-10: 0080861253
ISBN-13: 9780080861258
ISBN-10: 0444404023
ISBN-13: 9780444404022
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Has Professor Eccles investigated the effects of thiosemicarbazide or other convulsant agents on such presynaptic inhibitory mechanisms in the spinal cord? ADEY,W. ,DUNLOP, C. , KILLAM, K. F. and BRAZIER,M. A. B. In: Inhibition in the nervous system and gamma-aminobutyric acid. Pergamon, London, 1960: 3 17-323. R. JUNG: The most interesting features of presynaptic inhibition at sensory terminals, besides the mechanism of its postulated axon-axonal synapses seem to be its long duration and its large dipole potentiul Jield with electrotonic spread along the posterior roots.
ECCLES, J. , ECCLES, R. M. and MACNI,F. Central inhibitory action attributable to presynaptic depolarization produced by muscle afferent volleys. Physiol. ), 1961,159: 147-166. ECCLES,J. , FATT,P. and KOKETSU, K. Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurones. J. Physiol. ), 1954, 126: 524-562. ECCLES, J. , HUBBARD, J. I. and OSCARSSON, 0. Tntracellular recording from cells of the ventral spino-cerebellar tract. J. Physiol. ), 1961, 158: 486-516. ECCLES, J.
12. In general terms it can be stated that presynaptic inhibition provides the first stage in what we may term “perceptual attention”, whereby powerful sensory inputs with an implica- 1NHlRlTORY ACTIONS IN THE SPINAL CORD ‘C x 80. 60’ 0 0 100 100 100 300 300 su SP 400 500 5P su msec Fig. 13 Interaction of cutaneous volleys as revealed by dorsal root potentials (DRP) recorded as in Fig. 9 A . The rootlet was taken from the caudal part of LS dorsal root. A shows the control dorsal root potential (CON) generated by a SP volley and its inhibition by a preceding volley in SU at intervals given by the time scale.
Brain Mechanisms by Giuseppe Moruzzi, Alfred Fessard and Herbert H. Jasper (Eds.)
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