Read e-book online Centrally Acting Peptides PDF

By J. Hughes Ph.D. (eds.)

ISBN-10: 1349036684

ISBN-13: 9781349036684

ISBN-10: 1349036706

ISBN-13: 9781349036707

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An especially prominent group of neurons within the peri ventricular nucleus at caudal levels of the optic chiasma contain somatostatin. These neurons are located just deep to the ependyma and extend the height of the IIIrd ventricle, although they are more concentrated dorsally. Their axons project laterally and ventrally towards the mid-lateral aspect of the optic chiasma. A number of TRH cell bodies are also found within the nucleus. SP fibres are encountered here also. 2 Immunofluorescence micrographs of coronal sections of the rat perifornical area (a), hypothalamic pedventricuiat' area (b), piIiform cortex (c) and dorsal tegmental nucleus (d) after incubation with antiserum to methionine-enlc:ephalin, TRH, SOM and SP, respectively.

Immunohistochemistry of Pep tides 27 The dorsolateral substantia nigra has a population of ENK cell bodies. The zona compacta of the substantia nigra receives a number of ENK terminals, and ENK fibres are also closely associated with the medial lemniscus. On the other hand, SP fibres and terminals occur in very high concentrations in the zona reticulata of the substantia nigra. The motor nucleus of cranial nerve III has a component of TRH terminals. Rhombencephalon The cerebellum is essentially empty with respect to the peptides we have studied.

Reichlin), Raven Press, New York, (in press) Kuhar, M. , Pert, C. B. and Snyder, S. H. (1973). , Hlikanson, R. and Rehfeld, J. F. (1976). Proc. natn. Acad. , 73, 319-200 Lembeck, F. and Zetler, G. (1962). Int. Rev. , 4,159-215 Lien, E. , Fenichel, R. , Sarantakis, D. and Grant, N. H. (1976). , 19,837-40 Livett, B. , Uttenthal, 1. O. and Hope, D. B. (1971). Phil. Tans. R. Soc. , 261, 371-378 McCann, S. , Wheaton, J. and Moss, R. 1. 5). In Anatomical Neuroendocrinology (ed. W. E. Stumpf and 1. D.

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Centrally Acting Peptides by J. Hughes Ph.D. (eds.)

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