Download e-book for kindle: Dynamic Aspects of Conformation Changes in Biological by Bernard Pullman (auth.), Charles Sadron (eds.)

By Bernard Pullman (auth.), Charles Sadron (eds.)

ISBN-10: 9401025797

ISBN-13: 9789401025799

ISBN-10: 9401025819

ISBN-13: 9789401025812

On the day after the 1959 Cambridge Congress, within which the foreign Union of natural and utilized Biophysics used to be based, a biophysics part used to be shaped in the Society of actual Chemistry (Societe de Chimie Physique). on account that then, 3 of the Society's annual conferences (the eleventh, seventeenth, and twenty third) have been dedicated solely to the physico-chemical learn of organic structures. the 1st of those used to be held in June 1961 at a lodge in Col de Voza, on the foot of an alpine glacier above Chamonix. the second one, in may well 1967, happened within the extra realized atmosphere of the venerable rooms of the nationwide Museum of ordinary historical past in Paris. The 3rd - the only handled within the current quantity - was once lately held at Orleans-La resource within the newly equipped lecture theatres of the younger collage, that's close to the good Institutes of the nationwide Centre for clinical study (CNRS), at the Sologne plateau. those 3 levels are milestones of an evolution which characterises (at least schematically) the explosive evolution of organic physico-chemistry. the 1st colloquium, with the identify 'Deoxyribonucleic Acid: constitution, Synthesis and Functions', really marks the 1st touch of the actual chemist with one of many then such a lot prestigious organic macromolecules, the constitution of which had simply been came across, and during this approach celebrated one of many first and such a lot extraordinary successes of molecular biology.

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Additional info for Dynamic Aspects of Conformation Changes in Biological Macromolecules: Proceedings of the 23rd Annual Meeting of the Société de Chimie Physique Orléans, 19–22 September 1972

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BioI. 31, 269. Crippen, G. M. and Scheraga, H. : 1969, Proc. Nat. A cad. Sci. US 64,42. Bystrov, V. , Portnova, S. , Tsetlin, V. , Ivanov, V. , and Ovchinnikov, Yu. : 1969, Tetrahedron 25, 493. : 1971, Collection Czechoslov. Chem. COl11l11l1n. 36, 2474. Berthod, H. : 1971, Biochil11. Biophys. Acta 232, 595. Berthod, H. : 1971, Biochil11. Biophys. Acta 246, 359. : 1972, Biochil11. Biophys. Acta 1, 269. Saran, A. : 1971,1. Theoret. BioI. 33, 407 Sasisekharan, V. and Lakshminarayanan, A. : 1969, BiopolYl11ers 8, 505.

D) Sur la Figure 9 est representee la carte conformationnelle du residu alanyl donnee par Liquori [36] et a partir de laquelle il elabore son hypothese du code stereo chimique. 1 42/ys 84 85 ala glu 8s1eu 94 ala 95 thr 96/yS 97 hIS 98/ys ~~=r--P-~~--~------~~~~~------~----~ 44 43phe asp 99 fie 45arg 100 pro 46phe 118 arg his 47lyS 119 48 hIS r-------~~~~r_------r_------r_------r_----_149reU 120 pro 50lys 121 122 asn (hr 8·0 51 57 ala ~~Fs~~~+--+-+-~ I:::::: 58ser 77/ys 78 fys 79lyS 80gly hIs his r-----_1-------+-----+----f------t-----j 83glu 81 82 gly 123phe 124g~ aa 125 148gU 149 leu 150gly 151 152 153 (y'r glu gly 0~~~·4~~_&~~~ o 60 Fig.

Metres rotationnels. II faut ajouter a cela les 16 angles de rotation des chaines laterales. II est clair que Ie volume des calculs correspondants est considerable et on s'est contente au depart d'evaluations partielles de l'energie conformationnelle. Actuellement, on a bien mis en evidence l'existence de structures type comme Ie 'f3-turn' permettant la formation de liaisons H intramoh~culaires (Figure 11), qui aident beaucoup a la comprehension des conformations des cycles peptidiques. De Santis [54] a calcule la conformation de la gramicidine S en construisant une sequence des conformations locales les plus stables et en raffinant la conformation ainsi obtenue d'apres les resul- 46 MARIUS PTAK tats experimentaux d'une part, par minimisation de l'energie totale d'autre part.

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Dynamic Aspects of Conformation Changes in Biological Macromolecules: Proceedings of the 23rd Annual Meeting of the Société de Chimie Physique Orléans, 19–22 September 1972 by Bernard Pullman (auth.), Charles Sadron (eds.)

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