Download PDF by Colm McDonald: The Maudsley Family Study of Psychosis: A Quest for

By Colm McDonald

ISBN-10: 0203885252

ISBN-13: 9780203885253

ISBN-10: 1841697346

ISBN-13: 9781841697345

Psychotic issues akin to schizophrenia and bipolar sickness are recognized to be hugely heritable. regardless of many years of analysis, besides the fact that, the genetic adaptations conferring susceptibility to those health problems have not begun to be pointed out. Such genetic diversifications probably produce abnormalities of mind constitution and serve as from which the medical beneficial properties of psychosis emerge. The Maudsley kinfolk learn of Psychosis investigates the genetically produced markers of irregular mind constitution and serve as (‘intermediate phenotypes’) which underlie the medical syndrome of schizophrenia, and extra lately bipolar ailment. during this publication, key findings of this significant learn application, and their implications for this box, are mentioned intimately. individuals define study analyzing mind constitution and functioning in sufferers with schizophrenia and their unaffected first measure relations, incorporating particular scientific tests, magnetic resonance imaging, electrophysiology, eye monitoring measures and neuropsychology. This ebook presents a higher realizing of disease pathways and strength scope for intervention with a purpose to larger deal with and stop psychotic problems and should be of curiosity to teachers and clinicians within the box.

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Extra resources for The Maudsley Family Study of Psychosis: A Quest for Intermediate Phenotypes (Maudsley Monographs)

Example text

R. (1980). Morbidity risks of schizophrenia and affective disorders among ®rst degree relatives of patients with schizophrenia, mania, depression and surgical conditions. British Journal of Psychiatry, 137, 497±504. , et al. (2000). Increased morbid risk for schizophrenia in families of in-patients with bipolar illness. Schizophrenia Research, 42, 83±90. , Sauer, H. (1999). Genetic in¯uence on auditory 20 THE MAUDSLEY FAMILY STUDY OF PSYCHOSIS information processing in schizophrenia: P300 in monozygotic twins.

2002). Neuregulin 1 and susceptibility to schizophrenia. American Journal of Human Genetics, 71, 877±892. , et al. (2002). 3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. American Journal of Human Genetics, 71, 337±348. , et al. (2006). 1 in the combined sample. American Journal of Human Genetics, 78, 315±333. , et al. (2006). Evaluation of a susceptibility gene for schizophrenia: genotype based metaanalysis of RGS4 polymorphisms from thirteen independent samples.

Et al. (1994). The Finnish adoptive family study of schizophrenia: Implications for family research. British Journal of Psychiatry, 164, 20±26. , Collier, D. (2005). Association between the neuregulin 1 gene and schizophrenia: a systematic review. Schizophrenia Bulletin, 31, 613±617. R. (1980). Morbidity risks of schizophrenia and affective disorders among ®rst degree relatives of patients with schizophrenia, mania, depression and surgical conditions. British Journal of Psychiatry, 137, 497±504.

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The Maudsley Family Study of Psychosis: A Quest for Intermediate Phenotypes (Maudsley Monographs) by Colm McDonald


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